Field experiments were conducted at eleven centers of All India Coordinated Research Project on Potato located in different agro-climatic zones to investigate the role of phosphobacteria in P economy in potato crop during 2005-06 and 2006-07. Six treatments consisting of combinations of different levels of P as well as phosphobacteria (PSB) used in the study showed significant effect on yield of potato. At Kalyani, Chhindwara, Kota, Patna, Hassan and Ooty, recommended dose of NK + 75% P + PSB was statistically at par with recommended dose of NPK in term of total yield. At Bhubaneshwar, Dholi, Hisar, Deesa and Modipuram, 75% of fertilizer P + PSB either had no significant effect on potato tuber yield or reduced the yield marginally in two years of experimentations. Net returns with recommended NPK or 75% P + PSB showed the best results at most of the centers. The per cent saving of fertilizer P, calculated using quadratic model, was maximum for Hassan (43%). In general, use of PSB saved around 20 to 25% P, depending upon agro-ecological situations and soil conditions. However, at Bhubaneshwar, Kota and Dholi the saving being very meager was not economical. The results clearly indicate the role of PSB in saving fertilizer P across different agro-climatic zones, However, it also came out very clearly that effectiveness of the PSB depends on agro-ecological situations and soil conditions.